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Dyslipidaemia Global Newsletter #3 Dyslipi
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rationale and provided the patient agrees. In patients who have The USPSTF also provides the following disclaimer:
a cardiovascular risk factor and an estimated 10-year CVD “The USPSTF recognizes that clinical decisions involve
risk of 7.5% to less than 10%, the benefit of starting a statin more considerations than evidence alone. Clinicians should
is smaller, so clinicians should selectively offer a statin, taking understand the evidence but individualize decision-making to
patient values and preferences into account. For adults 76 years the specific patient or situation”.
or older, the evidence is insufficient to recommend for or against
starting a statin in primary prevention. LISTEN TO A PODCAST WITH THE
AUTHORS
In addition to the recommendations, the USPSTF comments
that men have a higher prevalence of CVD than women, FIND ADDITIONAL TOOLS AND
although women experience higher mortality from certain CV RESOURCES HERE
events. In addition, men experience CVD events earlier in life
compared with women. Among both sexes, Black persons CLICK HERE
have the highest prevalence of CVD. It is therefore essential FOR THE LINK TO FULL ARTICLE
to improve statin use in both women and men of all races and
ethnicities, and especially among Black and Hispanic adults,
who have the highest prevalence of CVD and the lowest
utilization of statins, respectively.

Long-term secondary prevention of cardiovascular disease with a Mediterranean
diet and a low-fat diet (CORDIOPREV): A randomised controlled trial.

Delgado-Lista J, et al. Lancet. 2022;399:1876-85.

Although some clinical guidelines recommend the Mediterranean diet for secondary prevention of cardiovascular disease, the
CORonary Diet Intervention with Olive oil and cardiovascular PREVention (CORDIOPREV) study is the first long-term, large-scale
clinical trial in the past 20 years to support this recommendation. In this hallmark study, 502 patients on the Mediterranean diet vs.
500 patients on a low-fat diet were followed for seven years and assessed for a composite of major cardiovascular events, including
MI, revascularization, ischemic stroke, peripheral artery disease, and cardiovascular death.

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